Particle Vision and Measurement (PVM)

Real-time microscopy allows scientists to directly observe particles, crystals and droplets as they naturally exist in process. By visualizing particles and particle mechanisms in real time, scientists acquire process knowledge that would otherwise prove too difficult or time consuming to obtain. This knowledge supports evidence-based decisions and decreases the cost of process development.

Particle View
View Inline Particle Size and Shape in Real Time With In Situ PVM images 
Particle View  with PVM (Particle Vision and Measurement) technology is a probe-based video microscope that visualizes particles and particle mechanisms as they exist in process.  High resolution images are continuously captured under a wide range of process conditions without the need for sampling or offline analysis. A process trend, sensitive to changes in particle size and concentration, is automatically combined with the most relevant images, providing scientists with a straightforward and reliable method to ensure comprehensive understanding is acquired with every experiment.

Study Particle Size and Shape
High resolution imaging of particles in real time enables scientists to determine the influence of process parameters on particle size and shape. Particles can be designed to behave predictably as key parameters change during development, scale-up and manufacturing.

Characterize Transient Events and Elusive Mechanisms

Particles and particle structures often change when sampled.  By visualizing crystals, droplets and other delicate particle structures inline, scientists can characterize transient events and elusive mechanisms that may be critical for optimizing the quality of a product or process.

Investigate Critical Process Events and Upsets 
An image-based trend, sensitive to changing particle size, shape and concentration, helps scientists identify and then investigate important process events and upsets.  The fast and reliable method reduces the time and effort needed to fully understand complex particle systems and processes.

Make Evidence-Based Decisions At a Lower Cost
By visualizing particles and particle mechanisms inline, scientists acquire knowledge that would otherwise prove too difficult or time consuming to obtain.  Such knowledge supports evidence-based decision making and process development at a lower cost.