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Advance Analytical
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Straightforward Raman Microscopy
The SENTERRA II defines a new level of spectroscopic performance and user friendliness in the class of compact Raman microscopes.
SENTERRA II is designed to deliver excellent sensitivity combined with high spectral and Raman Imaging performance. Therefore the SENTERRA II is a powerful platform for advanced research applications. Due to its high degree of automation, compact size and efficient workflow the SENTERRA II is likewise an ideal tool for solving real world tasks in the quality control laboratory.
Its unprecedented permanent stability of the wavenumber axis guarantees precise and accurate results at every time. The SENTERRA II is THE Raman microscope for both, the multi-user environment with high daily throughput and for the lab working at the forefront of scientific research.
SENTERRA II highlights:
- Research-grade spectroscopic performance
- Intuitive & convenient workflow due to software guidance and automated hardware
- Unmatched wavenumber accuracy and precision by SureCALTM
- Straightforward Raman imaging
- Compact design with spectrometer included in the microscope
- Full spectral range with all gratings
- Multi laser excitation with fast switching capabilities
- Combination with FT-Raman technology for minimized fluorescence
- Fully automated instrument tests according to USP 1120, PhEur 2.2.48, ASTM E1840 and E2529-06
- Full compliance with GMP/cGMP, GLP and 21 CFRp11
- Open architecture version for the study of larger samples (e.g. in art) with high lateral resolution
Applications of SENTERRA II
The SENTERRA II allows measuring Raman images and combines the obtained spatially resolved molecular information with high-quality microscopic images of the sample. The analysis is performed contactless and without the need of sample preparation. Chemical images of the sample surface can be achieved with a very high spatial resolution down to less than a micron. In addition depth profiling of optically transparent samples allows non-destructive sample investigation in the third dimension. Being suitable to be used for the detection, discrimination and identification of organic and inorganic materials the SENTERRA II has a wide range of applications.
Polymers
- Identification of pure polymers and blends
- Analysis of multilayer systems
- Characterization of polymers: crystallinity, density, conformation
- Determination of monomer content, fillers, additives
- Failure analysis: identification of impurities and inclusions
Pharmaceutical
- Differentiation of polymorphs
- Visualization of the distribution of API and excipients in tablets
- Failure analysis: Identification of particles & inclusions
Materials Science
- Differentiation of amorphous and microcrystalline silicon
- Characterization of novel 2D materials & carbon nanotube
Forensics
- Identification of trace evidence from crime scenes such as fibers, particles, paint chips, etc.
- Proof of the authenticity of works of art
- Analysis of counterfeit documents, pharmaceuticals and money
- Illicit drug analysis
Art and Cultural Heritage
- Identification of materials used for art objects
- Discrimination of genuine and fake artifacts
- Study of preservation, degradation and aging of objects of art
Life Science
- Study of the molecular composition of cells and tissue
Analysis of Microplastics using FTIR and Raman-Microscopy
FT-IR microscopy has established itself as the standard method for the analysis of MPP; it can be applied universally and enables a secure identification of all polymer types. Mapping measurements or FPA imaging allows determining thousands of MPPs in a fully automated manner.
Advantages of Raman Microscopy and Imaging in Pharmaceutical QC and R&D: an in-depth Review
Raman microscopy and imaging offers a straight answer to these questions. It can be employed on the testing of drugs in solid dosage forms, such as tablets and granules.
Raman Characterization of the Active Pharmaceutical Ingredients (APIs) in Nasal Sprays
Raman spectroscopy is one of the most commonly used techniques for materials identification and characterization, delivers a high amount of information on a molecular level and is applicable on almost any kind of pharmaceutical sample.
Raman-Troubleshooting and Failure Analysis of precision mechanics
Identification of small, unknown contaminants and pollutants is readly feasible by Raman microscopy.
Overcoming experimental challenges in Raman spectroscopy applied to art, archaeology and earth sciences
Raman spectroscopy offers some advantages when applied to art and archaeology as well as earth sciences
Raman Characterization of a Transdermal Patch
Raman microscopy can effortlessly identify different materials and also provide valuable information about layer thickness without sample preparation.
Contactless Characterization of Amorphous and Microcrystalline Silicon using Raman Micro Spectroscopy
Raman spectroscopy is an ideal method for the characterisation of the crystalline/amorphous fraction of thin film solar cells.
Reverse Engineering of Materials and Polymers Using Infrared and Raman microscopy
Infrared and Raman spectroscopy have proven to be valuable tools in the characterization of materials and products.
